ABSTRACT
The goal of the current research was to investigate the effect of aerobic exercise on C-reactive protein [CRP] and lipid profile in overweight-obese women with subclinical hypothyroidism. This study enrolled 23 women who suffered from subclinical hypothyroidism. Patients' average age was 41.08 +/- 6.56 years and BMI was > 25 kg/m2. Subjects, following medical screening, were objectively selected and randomly divided into two groups, control [N=13] and experimental [N=10]. Initially, patients' height, weight, BMI, waist ratio, and WHR were measured in addition to serum levels of cholesterol, triglycerides, HDL-C, LDL-C, CRP, T4 and TSH. Then, the experimental group participated in aerobic exercise. The control group received no intervention other than follow up. After 12 weeks all variables were remeasured. For intra group comparison of data t-test was used and for group comparison, we used the independent t-test [P
ABSTRACT
Retinol binding protein4 [RBP4] is a type of adipokine which transports vitamin A to serum. RBP4 could be a bridge between obesity and insulin resistance. This study aimed to investigate the effects of aerobic exercises on RBP4 serum's concentration and metabolic syndrome risk factors in obese women. Twenty obese women with body max index 35.81 +/- 3.67Kg/m2, fat percentage 43.98 +/- 4.02, and waist to hip ratio 1.03 +/- 0.05 were included and were randomly assigned to experimental and control groups. The experimental group received aerobic exercises for a period of 12 weeks each three sessions on treadmill workout. The treadmill speed were based on a 60-65 and 80-85 maximal heart rate percentage and duration of 15-20 and 45-50 minutes, at the beginning and the end of exercise, respectively. Body composition, serum glucose, insulin, TG, LDL-C, HDL-C, total cholesterol, and RBP4, were measured in both groups before and after the treatment by ELISA method. Insulin resistance was measured by HOMA-IR. To compare within group differences and between group comparisons t-correlated and t-independent tests were used, respectively. After 12 week aerobic exercises; weight, fat percentage, WHR, and BMI in the experimental group was significantly decreased [P<0.05]. RBP4, insulin, insulin resistance, TG and HDL-C had significant differences between two groups. The cholesterol level, LDL-C and glucose did not have any significant changes. The aerobic exercises can decrease body composition, insulin resistance, TG, and RBP4, so it can be beneficial for obese women's health, because it